My game was crashing whenever I tried going from one area to another, and I found out a way to fix that.
I was playing the game with Windows XP, so I tried playing it with Windows 7 x64 and all my zone-change crashes stopped. Not sure if the OS is to blame, or if I just had weird drivers installed on my XP PC...
So, you can try playing on another computer with a different operating system, or try messing around with your video card and sound card drivers, maybe?
Sorry, I'm not a very good tech.